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KMID : 0812020080140020140
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Korean Journal of Neurogastroenterology and Motility
2008 Volume.14 No. 2 p.140 ~ p.144
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A Case of Multiple System Atrophy Presenting with Esophageal Dysphagia
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Park Hye-Won
Jung Hwoon-Yong
Lee Dan-Bi
Kim Do-Hoon
Jung Kee-Wook
Chung Jun-Won
Choi Kwi-Sook
Choi Kee-Don
Song Ho-June
Kim Jin-Ho
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Abstract
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Dysphagia occurs frequently as an accompanying sign of neurodegenerative disorders. Degeneration of the dorsal vagal motor nucleus may cause esophageal dysphagia. Multiple system atrophy (MSA) is a progressive neurodegenerative disorder of unknown etiology. Dysphagia is one well-recognized complication of MSA and is closely related to the prognosis of patients. However, the swallowing function of patients with MSA has not been explored systematically. We experienced a 73-year-old male who had recurrent syncope with dysphagia. Neurologic examinations revealed a cerebellar dysfunction and autonomic function tests were abnormal. We diagnosed this case as MSA. The esophagogastroscopy was normal and the esophageal manometry revealed low pressure of the upper esophageal sphincter and lack of normal peristalsis. Barium esophagography showed ineffective primary peristalsis and weak tertiary peristalsis. We considered that diagnosis of dysphagia caused by degeneration of autonomic cranial nerves.
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KEYWORD
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Dysphagia, Multiple system atrophy, Manometry, Autonomic function
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